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The 49ers stay undefeated through 4 weeks, and what higher approach to take a look at their mettle than against the reigning Super Bowl champions?
San Francisco’s 4-0 begin contains wins over elites such as the Rams and Broncos, while Seattle’s 3-1 mark has come from a softer schedule.
With three clear-cut Super Bowl contenders, it’s fairly secure to say that the path to a Lombardi Trophy runs through the NFC West, and these divisional video games will carry important weight in the NFL’s hierarchy.
The twelfth Man at Lumen Field ostensibly bears more weight than Brock Purdy’s MVP marketing campaign as the Seahawks are 3.5-point favorites. The two cut up last season’s conferences, while the Seahawks haven’t crushed the 49ers at home in the common season since 2021.
49ers vs. Seahawks prediction, finest guess
San Francisco isn’t with out considerations. Nick Bosa stays sidelined, Kyle Juszczyk is uncertain, and Mike Evans is dealing with a rib damage.
But the 49ers’ backyard is still in full bloom: the offense has flourished through the air and on the floor, while the protection has continued to stifle opponents despite these varieties of key accidents. Years of continuity with this veteran core have cultivated a degree of management and cohesion.
Sam Darnold #14 of the Seattle Seahawks reacts against the Los Angeles Chargers after the recreation at Lumen Field on October 04, 2026 in Seattle, Washington. Getty Images
Just how good has Purdy been? His passing attack is averaging an extraordinary 0.48 EPA per try, almost double Baltimore’s second-ranked mark of 0.27. He’s also yet to take a sack this season with Kyle Shanahan’s offense structured around fast selections and manageable throwing home windows.
Defensively, the Seahawks stay impenetrable, main the NFL in yards allowed. On offense, they’re not fairly the crisp operation as we expected — particularly with out Kenneth Walker. The Seahawks rank twenty ninth in speeding EPA and are with out beginning working back Jadarian Price, leaving Sam Darnold more and more dependent on his passing recreation.
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Darnold’s put up massive numbers against Washington with Jaxon Smith-Njigba in Week 3, ending his return from a glute damage with 379 passing yards and 4 touchdowns, but he threw two expensive interceptions, one of which was a pick-six that handed the lead to Washington with under 5 minutes left.
Last week, Seattle wanted a muffed punt and Smith-Njigba’s brilliance to separate from the Chargers last week.
Against a more environment friendly opponent, relying on these circumstances is a harmful proposition.
We know this will be a tightly contested battle. So, why take the factors when you can seize San Francisco outright for plus cash?
THE PLAY: 49ers moneyline (+136, DraftKings)
Why Trust New York Post Betting
Sean Treppedi handicaps the NFL, NHL, MLB and school soccer for the New York Post. He primarily focuses on picks that replicate market worth while monitoring tendencies to mitigate danger.
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